sábado, 13 de abril de 2013

A brief history of psychosurgery

To all doctors, we need a little history of medicine. We must learn the past to change the future.
In April 05, 2013, the periodic Surgical Neurology International published a very interesting article about the history of psychosurgery. The author describes the trepanations done in Peru by the Incas to cure mental illness and the respective tools used. He talks about the case of Gage, the man who acquired mental impairment after penetrating brain injury to the frontal lobe. The case become famous and is called "American Crowbar Case". From being a motivated, energetic, capable, friendly, and conscientious worker, Gage changed dramatically into an obstinate, irreverent, irresponsible, socially uninhibited individual. These changes in personality would later be recognized as the frontal lobe syndrome. The author talks about "the lobotomist", Dr. Walter Freeman (1895-1972), who has made transorbital leucotomy by using a modified ice-pick instrument to traverse the roof of the orbit and enter the base of the skull with local anesthesia. Freeman hoped that physicians would use this simple technique to treat hospitalized patients widely.  Many physicians became disappointed with the results, as some patients developed complications or died. But the majority of patients were improved, severe symptoms ameliorated, most families were gratified, and institutionalized patients became more manageable in the various institutions.
Recently, the BBC News showed mentally ill patients held in chains in Indonesia as the picture below. The question is, how should we treat these patients so humanized? Their families need help too. Click in the link to read this news.

Mentally ill patients held in chains
 
 
 
Abstract:
 
Psychosurgery was developed early in human prehistory (trephination) as a need perhaps to alter aberrant behavior and treat mental illness. The "American Crowbar Case" provided an impetus to study the brain and human behavior. The frontal lobe syndrome was avidly studied. Frontal lobotomy was developed in the 1930s for the treatment of mental illness and to solve the pressing problem of overcrowding in mental institutions in an era when no other forms of effective treatment were available. Lobotomy popularized by Dr. Walter Freeman reached a zenith in the 1940s, only to come into disrepute in the late 1950s. Other forms of therapy were needed and psychosurgery evolved into stereotactic functional neurosurgery. A history of these developments up to the 21st century will be related in this three-part essay-editorial, exclusively researched and written for the readers of Surgical Neurology International (SNI).
Keywords: Frontal lobes, institutionalization, lobotomy, mentally ill, psychosurgery, trephination
 
Author: Miguel A Faria
Clinical Professor of Neurosurgery (ret.) and Adjunct Professor of Medical History (ret.), Mercer University School of Medicine; President, www.haciendapub.com, Macon, Georgia, USA
 
The Extraction of The Stone of Madness (or The Cure of Folly) by Hieronymus Bosch. Museo del Prado, Madrid, Spain

Dr. Walter Freeman and the frontal transorbital lobotomy


How to cite this article:
Faria MA. Violence, mental illness, and the brain - A brief history of psychosurgery: Part 1 - From trephination to lobotomy. Surg Neurol Int 2013;4:49
 

How to cite this URL:
Faria MA. Violence, mental illness, and the brain - A brief history of psychosurgery: Part 1 - From trephination to lobotomy. Surg Neurol Int [serial online] 2013 [cited 2013 Apr 13];4:49. Available from: http://www.surgicalneurologyint.com/text.asp?2013/4/1/49/110146

Dr. Bernardo de Andrada
be.andrada@yahoo.com.br

segunda-feira, 1 de abril de 2013

Incidence of Neurosurgical Wrong-Site Surgery

Artigo publicado na revista Neurosurgery de Abril de 2013 por Jay Vaccani sobre a incidência de neurocirurgias realizadas do lado errado. A incidência de craniotomias do lado errado chega de 2 a 3 por 10.000 nos Estados Unidos.
 
 
Abstract
BACKGROUND: Although exceedingly rare, wrong-site surgery (WSS) remains a persistent problem in the United States. The incidence is thought to be 2 to 3 per 10 000 craniotomies and about 6 to 14 per 10 000 spine surgeries. In July 2004, the Joint Commission mandated the Universal Protocol (UP) for all accredited hospitals.
OBJECTIVE: To assess the effect of UP implementation on the incidence of neurosurgical WSS at the University of Illinois College of Medicine at Peoria/Illinois Neurological Institute.
METHODS: The Morbidity and Mortality Database in the Department of Neurosurgery was reviewed to identify all recorded cases of WSS since 1999. This was compared with the total operative load (excluding endovascular procedures) of all attending neurosurgeons to determine the incidence of overall WSS. A comparison was then made between the incidences before and after UP implementation.
RESULTS: Fifteen WSS events were found with an overall incidence of 0.07% and Poisson 95% confidence interval of 8.4 to 25. All but one of these were wrong-level spine surgeries (14/15). There was only 1 recorded case of wrong-side surgery and this occurred after implementation of the UP. A statistically greater number of WSS events occurred before (n = 12) in comparison with after (n = 3) UP implementation (P < .001).
CONCLUSION: A statistically significant reduction in overall WSS was seen after implementation of the UP. This reduction can be attributed to less frequent wrong-level spine surgery. There was no case of wrong procedure or patient surgery and the 1 case of wrong-side surgery occurred after UP implementation.
ABBREVIATIONS: JC, Joint Commission
UP, Universal Protocol
WSS, wrong-site surgery
 
Author Information
Department of Neurosurgery, Illinois Neurological Institute, University of Illinois College of Medicine in Peoria, Peoria, Illinois
Correspondence: Jay A. Vachhani, MD, Department of Neurosurgery, Illinois Neurological Institute, University of Illinois College of Medicine in Peoria, 530 NE Glen Oak Ave, Peoria, IL 61637. E-mail: jay.vachhani@gmail.com
Received May 24, 2012
Accepted December 04, 2012

Full article:
http://journals.lww.com/neurosurgery/Fulltext/2013/04000/Incidence_of_Neurosurgical_Wrong_Site_Surgery.19.aspx
 

domingo, 24 de março de 2013

Nossos Crânios em Evolução


Esses dias passando pelas imediações de São Cristóvão e gozando da raridade de um tempo a mais decidi passar no Museu Nacional, um casarão na bastante arborizada Quinta da Boa Vista. O museu ocupa o imóvel da antiga residência da família real no Rio de Janeiro, pertence à UFRJ (Universidade Federal do Rio de Janeiro) e reúne um dos maiores acervos científicos da América Latina. Nesse passeio pelas aulas de biologia do ginásio o que mais me chamou a atenção foram os fósseis de crânios dos nossos ancestrais, que me fez refletir bastante sobre toda a evolução até chegarmos ao presente homo sapiens e a era da internet.

Observando nossos ancestrais e até mesmo os macacos, percebo como ao mesmo tempo somos tão semelhantes e tão diferentes. Essa diferença toda é sem dúvida originada no desenvolvimento do cérebro, que nos permitiu evoluir de simples habilidades manuais para as habilidades filosóficas, matemáticas e científicas em geral. O desenvolvimento do crânio nos tornou conscientes e então viemos conhecer o que realmente somos ou, pelo menos, estamos tentando bolar algumas teorias acerca disso ao longo da história.

Na era das redes sociais poderíamos nos surpreender com o fato de que andar de forma “erecta” foi considerado uma habilidade um dia e caracterizou uma espécie hominídea. Após lascarmos a pedra no período paleolítico para criarmos instrumentos de caça e pesca, escrevemos nossos diários rupestres em paredes de cavernas contando nossos sucessos e fracassos nas caçadas selvagens. Os períodos históricos passaram e conseguimos executar obras faraônicas no Egito, contar com a contribuição de tradições de povos e pessoas (filósofos) que dedicaram a vida a pensar e tentar responder perguntas até encontrarem a razão. É interessante pensar como o sistema nervoso evoluiu de maneira centrípeta, ou seja, primeiro os nervos periféricos seguidos pela medula, que foi acompanhada do desenvolvimento da coluna vertebral e nos permitiu ser homo erectus. Depois veio o desenvolvimento do cérebro, principalmente do telencéfalo, que nos deu um sobrenome que faz alusão ao saber, a sapiência, e um crânio capaz de suportar um maior volume de neurônios. Carregamos até hoje habilidades como pensar, saber, raciocinar, filosofar, debater e concluir. Essas foram aquisições tão importantes na evolução que nos fez mudar o nome da espécie, homo sapiens sapiens, e daqui a algum tempo terão que acrescentar mais alguns sapiens no nome já que a geração video-game vem desenvolvendo muito o intelecto, além dos reflexos e da habilidade de raciocinar rapidamente. Por esse motivo as crianças nos parecem cada vez mais espertas e prometem muitas mudanças no comportamento da humanidade em um futuro bem breve.

Atualmente participamos de uma nova era, a da consciência coletiva. Temos ciência das diversas opiniões através de blogs e do facebook e somos sozinhos capazes de formar uma opinião própria, sem contarmos com a ajuda de grandes correntes manipuladoras. Contando cada vez mais com a ajuda da internet, entramos na era da liberdade da informação, quando processamos informações brutas vindo de diversos veículos de comunicação e formamos uma massa cada vez mais maciça de conclusões personalizadas em nossa mente. O intuito coletivo apesar de reprimido outrora sempre escapa em busca da evolução por outra passagem, atualmente representada pela internet, uma luz no fim do túnel. Nos dias atuais me pergunto como pode um mundo que se considera em evolução filosófica ainda sofrer feridas que sangram causadas pela inveja, raiva, ciúmes e outros sentimentos ruins?

A diferença no tamanho do crânio entre nós e nossos ancestrais não é mera coincidência. Será que teremos uma cabeça maior em um futuro onde o homem respeitará e viverá em paz com o próximo?

"Os males não cessarão para os humanos antes que a raça dos puros e autênticos filósofos chegue ao poder, ou antes, que os chefes das cidades, por uma divina graça, ponham-se a filosofar verdadeiramente." (Platão, Carta Sétima, 326b).


 
 Crânio do Australopitecus
 Crânio de um Homo Erectus
Australopitecus


Aos que forem visitar o Rio de Janeiro recomendo a visita, parece que estão fazendo melhorias e obras de restaurações. http://www.museunacional.ufrj.br/
 
Bernardo de Andrada

sábado, 2 de março de 2013

O PLEXO BRAQUAL / THE BRACHIAL PLEXUS

My new frame in acrylic paint.
The brachial plexus.



 

Dr. Bernardo de Andrada
Neurocirurgião

domingo, 24 de fevereiro de 2013

SÓ SEI QUE NADA SEI

 
 
"Só sei que nada sei" - Sócrates 
 
Sem sombra de dúvidas é a mais pura verdade sobre o universo de neurônios que é o sistema nervoso, e também sobre as ciências que tentam desvendá-lo. Atuando nessa área posso me sentir como um verdadeiro astronauta em relação ao espaço e suas estrelas e planetas.
 
O cérebro me atraiu muito não só na medicina...
 
Dr. Bernardo de Andrada
 
 

domingo, 27 de janeiro de 2013

SCALES AND CLASSIFICATIONS - NEUROSURGERY

Coletânea das escalas e classificações mais úteis em neurocirurgia
Collection of more useful scales and classifications in neurosurgery
 
Karnowsky:
100% – normal, no complaints, no signs of disease
90% – capable of normal activity, few symptoms or signs of disease
80% – normal activity with some difficulty, some symptoms or signs
70% – caring for self, not capable of normal activity or work
60% – requiring some help, can take care of most personal requirements
50% – requires help often, requires frequent medical care
40% – disabled, requires special care and help
30% – severely disabled, hospital admission indicated but no risk of death
20% – very ill, urgently requiring admission, requires supportive measures or treatment




Wiltse Classification

Classification of Spondylolisthesis
1.) Dysplastic : Congenital malformation of the sacrum or neural arch of L5.
2.) Isthmic: Stress fracture, elongation, or acute fracture of the pars.
3.) Degenerative: Long-standing arthritic process of the zygapophyseal joints.
4.) Traumatic: Neural arch fracture excluding the pars region.
5.) Pathologic: Bone disease – Paget’s, Metastatic disease, or Osteopetrosis.
6.) Iatrogenic: Following lumbar spine surgery

Reference: Wiltse LL, Newman PH, Macnab I. “Classification of spondylolysis and spondylolisthesis.” Clin Orthop Relat Res. 1976 Jun;(117):23-9.




WFNS grade for SAH


Grade
GCS
Motor deficit
I
15
-
II
14-13
-
III
14-13
+
IV
12-7
+/-
V
6-3
+/-




Simpson grade for meningioma resection:

 
 
 
MRC scale
0 – no movement
1 – flicker is perceptible in the muscle
2 – movement only if gravity eliminated
3 – can move limb against gravity
4 – can move against gravity & some resistance exerted by examiner
5 – normal power
 
MODIC CHANGES:
 
Modified Rankin Scale
The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke.'
 
 
0
No symptoms at all
1
No significant disability despite symptoms; able to carry out all usual duties and activities
2
Slight disability; unable to carry out all previous activities, but able to look after own affairs without assistance
3
Moderate disability; requiring some help, but able to walk without assistance
4
Moderately severe disability; unable to walk without assistance and unable to attend to own bodily needs without assistance
5
Severe disability; bedridden, incontinent and requiring constant nursing care and attention
6 Dead
 
Escala de McCormick modificada para tumors espinhais
Modified McCormick scale
I
Intact neurologically, normal ambulation, minimal dyesthesia
II
Mild motor or sensory deficit, functional independence
III
Moderate deficit, limitation of function, independent w/external aid
IV
Severe motor or sensory deficit, limited function, dependent
V
Paraplegia or quadriplegia, even w/flickering movement
 
Meyerding grade
Spondylolisthesis
Categorises severity of spondylolisthesis based upon measurements on lateral X-ray of the distance from the posterior edge of the superior vertebral body to the posterior edge of the adjacent inferior vertebral body. This distance is then reported as a percentage of the total superior vertebral body length:
§  Grade 1 is 0–25%
§  Grade 2 is 25–50%
§  Grade 3 is 50–75%
§  Grade 4 is 75–100%
§  Over 100% is Spondyloptosis, when the vertebra completely falls off the supporting vertebra.
 
Facial palsy in acoustic neuromas: House-Brackmann
 
 
 
 
Glasgow Outcome Scale
Outcome after sever brain damage
1. Dead
2. Persistent vegetative state (no obvious cortical function)
3. Severe disability (conscious but diabled)
 
4. Moderate disability (disabled but independent)
5. Good recovery (return to normal activities wvwn with minor neuro or psychological deficits)
 
 
Frankel Grade
Spinal Cord Function
A complete paralysis
B sensory function only below the injury level
C incomplete motor function below injury level
D fair to good motor function below injury level
E normal function
 
Fischer:
 
Cervical Myelopathy
1. Nurick’s classification system for myelopathy on the basis of gait abnormalities
Grade
Root signs
Cord involvement
Gait
Employment
0
Yes
No
Normal
Possible
I
Yes
Yes
Normal
Possible
II
Yes
Yes
Mild abnormality
Possible
III
Yes
Yes
Severe abnormality
Impossible
IV
Yes
Yes
Only with assistance
Impossible
Reference: Nurick S. The pathogenesis of spinal cord disorder associated with cervical spondylosis. Brain 1972; 95: 87-100
2. Ranawat Classification of Neurologic Deficit
Asia
Muscle strength is graded as
§  0 Total paralysis
§  1 - Palpable or visible contraction
§  2 - Active movement, full range of motion, gravity eliminated
§  3 - Active movement, full range of motion, against gravity
§  4 - Active movement, full range of motion, against gravity and provides some resistance
§  5 – Active movement, full range of motion, against gravity and provides normal resistance [Muscle able to exert, in examiner’s judgement, sufficient resistance to be considered normal if identifiable inhibiting factors were not present]
§  NT – not testable. Patient unable to reliably exert effort or muscle unavailable for test-ing due to factors such as immobilization, pain on effort or contracture.
 
 
ASA
  Presurgical condition for anaesthesia
§  1. Normal healthy patient
§  2. Mild systemic disease
§  3. Severe systemic disease
§  4. Severe systemic disease that is a constant threat to life
§  5. Moribund patient, not expected to survive the operation
§  6. Declare brain-dead patient whose organs are being removed for donor purposes
 
Hunt-Hess
Spetzler e Martin:
 
The Spetzler-Martin AVM grading system allocates points for various features of intracranial AVM's to give a score between 1 and 5. Grade 6 is used to describe inoperable lesions. The score correlates with operative outcome.

The grading system

  • size of nidus
    • small (<3cm) = 1
    • medium (3 - 6cm) = 2
    • large (> 6cm) = 3
  • eloquence of adjacent brain
    • non-eloquent = 0
    • eloquent = 1
  • venous drainage
    • superficial only = 0
    • deep = 1
 
 
 
 
 
Dr. Bernardo de Andrada